Five serious crashes in 12 hours, including two in the Chichester area, have prompted West Sussex Fire and Rescue to issue a safety warning.
Drivers are being urged to avoid the ‘fatal four’ - the four most common causes of road accidents in the UK.
The warning follows serious crashes on the A27 between Chichester and Havant and in Pagham.
There was also a crash involving a car and an articulated lorry on the M23, and serious collisions in Henley and Horsham.
The fatal four are inappropriate speed, using a mobile phone while driving, not wearing a seatbelt and drink/drug driving, a spokeswoman for the fire service said.
Motorists are also being urged to carry out basic vehicle checks, such as checking tread depth and tyre pressure.
Adrian Murphy, area manager for protection at West Sussex Fire And Rescue Service, said: “It was a busy end to the weekend for our crews and the other emergency services.
“Please take care on the roads so we can avoid a repeat of the number of incidents we have experienced.
“It so important that people are aware and remind themselves about the ‘fatal four’ - speed, distraction, seatbelts and drink and drug use. It’s not worth the risk.”